AstraZeneca
Associate Principal Scientist, Vaccine Drug Product Development
$138K–$208K
US - Gaithersburg - MD · Principal · Full-time · Posted Oct 27, 2026
- Experience
- BS: 10+ years; MS: 7+ years; PhD: 5+ years of experience in biopharmaceutical or vaccine development.
- Education
- BS, MS, or PhD in Biochemistry, Chemistry, Chemical/Biochemical Engineering, Immunology, Pharmaceutics or related fields of study.
About the job
Leads vaccine formulation and drug product process development from early research through pivotal clinical development and manufacturing readiness, shaping CMC strategy and coordinating internal and external teams.
What you'll do
- Lead formulation, process scale-up, characterization, and GMP manufacturing readiness for vaccine products.
- Set CMC and regulatory strategies, author or review submission content, and make evidence-based program recommendations.
- Lead technology transfer and external partners; support clinical and GMP batches and mentor scientists.
What they ask for
- Hands-on experience with one or more of these modalities: Bioconjugates, VLPs, mRNA-LNPs, recombinant protein vaccines.
- Expertise in vaccine adjuvant systems and co-formulated multi-antigen/adjuvant products.
- Track record in GMP manufacturing, tech transfer to CMOs/CDMOs, and clinical supply support.
- BS, MS, or PhD in a stated relevant field; required experience varies by degree.
Pay
USD 138,393 to USD 207,589 annual base salary
Tools
DLS, chromatography, mass spectrometry, spectroscopy, binding assays, thermal analysis, INDs, BLAs
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