AstraZeneca
Director, Oncology Bioanalytical Strategy Lead
$175K–$263K
US - Cambridge Kendall SQ - MA · Director · Full-time · Posted Oct 28, 2026
- Experience
- 10+ years with a bachelor’s degree; OR 7+ years with a master’s degree.
- Education
- Bachelor’s or master’s degree in immunology, molecular biology, or related studies.
About the job
Leads bioanalytical strategy and delivery for oncology programs, overseeing assay development, validation, scientific execution, and regulatory support across internal teams and external partners.
What you'll do
- Lead bioanalytical strategy and serve as IBA project team lead for selected programs across multiple modalities.
- Oversee assay design, development, validation, transfer, study conduct, data interpretation, and delivery with laboratory and CRO partners.
- Support regulatory submissions and health authority responses, and contribute to scientific publications, presentations, and strategic initiatives.
What they ask for
- Proven regulated bioanalysis expertise across PK, PD, and humoral and cellular immunogenicity assessments.
- Experience leading bioanalytical strategy in diverse project teams and with complex biologics and/or ADC bioanalysis.
- Bachelor’s degree in immunology, molecular biology, or related studies with 10+ years of relevant experience; OR master’s degree in those fields with 7+ years of relevant biopharmaceutical industry experience.
- Experience with regulatory expectations and filings, CRO assay transfer and study conduct, and stakeholder collaboration.
Nice to have
- Experience with radioconjugates, cell therapy, or small molecules; experience with ADCs, radioconjugates, or T-cell engagers is also described as highly desirable.
- Strong immunology background, deeper flow cytometry expertise, and experience improving bioanalytical operations with CROs.
Pay
$175,498.40 - $263,247.60 USD Annual (base pay)
Tools
Ligand binding assays, LC-MS, ddPCR, qPCR, RT-qPCR, flow cytometry, ELISpot, cytokine assays
Model-written summary · the original posting is authoritative