AstraZeneca
Postdoctoral Fellow 2025: AI-Informed Bioengineered Models for Predicting Human Response to mRNA Nanomedicines and Vaccines
$100K–$108K
US - Gaithersburg - MD +1 · Full-time · Posted Apr 20, 2025
- Location
- US - Gaithersburg - MD
US - Washington - DC - Experience
- Maximum of 4 years of prior postdoctoral research experience; minimum of 4 years developing and characterizing cell/biomaterial-based micro-physiological/microfluidic in vitro models.
- Education
- PhD in Bioengineering/Chemical Engineering or related quantitative field with specialization in biomaterials/tissue engineering.
About the job
Develop an AI-informed bioengineered micro-physiological model to predict human responses to mRNA nanomedicine and vaccine candidates.
What you'll do
- Design and develop micro-physiological models and methods to collect and analyze model readouts.
- Analyze omics readouts and contribute to applying AI tools to establish human-predictive capabilities.
- Drive the research project, publish scientific papers, and present at scientific meetings.
What they ask for
- PhD in Bioengineering, Chemical Engineering, or a related quantitative field, specializing in biomaterials/tissue engineering; PhD completion requirements must be finalized before the start date.
- Maximum of 4 years of prior postdoctoral research experience and minimum of 4 years developing and characterizing cell/biomaterial-based micro-physiological or microfluidic in vitro models.
- Expertise in 2D and 3D cell culture/cell reprogramming, primary cell types, bio-analysis techniques, and biomaterial-based tissue-engineering scaffolds.
- Proficiency in Python or a comparable language, data handling and visualization, statistical analysis, and at least 1 first/co-first author publication.
Nice to have
- Knowledge of immunobiology and experience with immune phenotyping using omics approaches.
- Hands-on AI/ML experience, including high-dimensional data analytics and data modeling.
Pay
US$99,900 up to Max of US$107,500 (base salary)
Tools
Python, Flow Cytometry, Confocal Microscopy, PCR, multiplex ELISA, AI/ML
AI focus
Apply AI tools and advanced data analytics to omics and model readouts to establish human-predictive capabilities; developing AI tools is optional.
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