Basecamp Research
Scientist I, Discovery
$110K–$140K
Boston · On-site · Full-time · Posted Oct 2, 2026
- Education
- PhD in molecular biology, biochemistry, genetics, bioengineering, or a life-sciences-related field, or an MSc with equivalent hands-on laboratory experience.
About the job
Develops and screens gene-editing tools and optimizes candidates for therapeutic development, collaborating with data science and AI teams.
What you'll do
- Designs, builds, tests, validates, and engineers novel gene-editing proteins and tools.
- Builds plasmid libraries and scalable cloning workflows; quantifies editing outcomes using molecular and sequencing assays.
- Optimizes activity and specificity in human primary cells and cell lines, and helps establish lab documentation and SOPs.
What they ask for
- PhD in molecular biology, biochemistry, genetics, bioengineering, or a life-sciences-related field, or an MSc with equivalent hands-on laboratory experience.
- Experience with gene editing, NGS assay development, protein engineering, and cell therapy.
- Experience with high-throughput cloning and DNA-construct production for cellular screening; mammalian cell culture, transfection, and cell-line generation.
- Expertise in DNA/RNA extraction, PCR, ddPCR, NGS library preparation and QC; knowledge of gene-editing technologies and on/off-target analytics.
Nice to have
- Experience contributing to a preclinical cell therapy program; flow cytometry expertise.
- Experience integrating AI protein design tools with high-throughput wet-lab screening; NGS instrumentation, bioinformatics, or traceable data pipelines.
Pay
USD $110K - $140K base salary; USD $110K – $140K (Compensation; type not specified)
Tools
ddPCR, qPCR, flow-cytometry, NGS, PCR
AI focus
Collaborates with Data Science and AI teams; preferred experience integrating AI protein design tools with high-throughput wet-lab screening.
Model-written summary · the original posting is authoritative