Basecamp Research
Scientist, Peptide Discovery
$110K–$165K
Boston · On-site · Full-time · Posted Oct 2, 2026
- Education
- PhD in molecular biology, biochemistry, microbiology, genetics, bioengineering, or a life-sciences-related field, or an MSc with equivalent hands-on laboratory experience.
About the job
Validates AI-generated peptide candidates through cell-based functional, safety, and developability assays, and feeds experimental results into peptide discovery programs.
What you'll do
- Run mammalian cell culture and cell-based assays, including cytotoxicity, hemolysis, permeability, and receptor activation testing.
- Analyze dose-response results, document findings, and develop assay strategies for peptide candidates.
- Collaborate with computational and AI teams to guide peptide down-selection and follow-up testing.
What they ask for
- PhD in a life-sciences-related field, or an MSc with equivalent hands-on laboratory experience.
- Demonstrated hands-on mammalian cell culture experience.
- Flow cytometry expertise using antibody panels and fluorescent reporters.
- Experience with cell-based functional or signaling assays, such as cAMP, GPCR activation, or reporter gene assays.
Nice to have
- Direct experience with GLP-1R or other incretin receptor assays, or stable receptor-expressing cell lines.
- Experience with Biacore (SPR), peptide handling, or antimicrobial/antifungal susceptibility testing.
Pay
USD 110K - 165K base salary
Tools
HepG2, HEK293, CHO, CellTiter Blue, HTRF, ELISA, Biacore (SPR), flow cytometry
AI focus
Experimentally validates AI-generated peptide candidates and shares results with computational/AI teams to inform iterative peptide down-selection; the posting also encourages intentional use of AI tools.
Model-written summary · the original posting is authoritative