Basecamp Research
Senior Scientist / Associate Director, T Cell Immunology
$140K–$220K
Boston · On-site · Director · Full-time · Posted Oct 16, 2026
- Experience
- Typically 6+ years post-PhD for Senior Scientist or 9+ for Associate Director; MSc with equivalent hands-on experience is an alternative.
- Education
- PhD in immunology, molecular biology, bioengineering, or a related life-sciences field, or an MSc with equivalent hands-on experience.
About the job
Own T cell immunology strategy and experimental work for in vivo cell therapy programs in oncology and autoimmunity, from primary human cell assays through IND-enabling studies.
What you'll do
- Design and run primary human T cell potency and specificity assays, and establish criteria for candidate selection.
- Lead translation into mouse and NHP studies, including CRO oversight and pharmacology, safety, and regulatory-filing work.
- Represent program data in agency and partner interactions, and mentor scientists as the team grows.
What they ask for
- PhD in immunology, molecular biology, bioengineering, or a related life-sciences field, with substantial industry experience in cell or gene therapy; or an MSc with equivalent hands-on experience.
- Hands-on expertise in primary human T cell biology and gene editing in primary immune cells.
- Expertise in multiparameter flow cytometry, including panel design and analysis.
- Fluency with ddPCR, qPCR, NGS library preparation and QC, and interpretation of on/off-target analytics; experience designing and overseeing in vivo mouse studies, including CRO management.
Nice to have
- Direct contribution to an IND or equivalent regulatory filing and first-hand knowledge of the pharmacology and toxicology package.
- NHP study design and oversight; working knowledge of regulatory expectations for genome-edited cell and gene therapies.
Pay
$140K - $220K USD base salary
Tools
ddPCR, qPCR, NGS, multiparameter flow cytometry, spectral flow cytometry, CROs, GLP
AI focus
Work with AI teams to characterize novel editing enzymes in primary human T cells and define potency and specificity criteria for candidate selection.
Model-written summary · the original posting is authoritative