Basecamp Research
Senior Scientist Peptide Discovery
$110K–$165K
Boston · On-site · Senior · Full-time · Posted Oct 20, 2026
- Education
- PhD in molecular biology, biochemistry, microbiology, genetics, bioengineering, or a life-sciences related field, or an MSc with equivalent hands-on laboratory experience.
About the job
Validates AI-generated peptide candidates through cell-based functional, safety, and developability assays, and uses experimental results to guide peptide discovery.
What you'll do
- Perform mammalian cell culture and cell-based assays for peptide activity, cytotoxicity, hemolysis, permeability, and safety.
- Develop assay strategies, analyze dose-response data, and document results; support fungal susceptibility testing and peptide handling.
- Collaborate with AI and computational teams to inform candidate selection; mentor junior staff and help prioritize assay development.
What they ask for
- PhD in a life-sciences related field, or an MSc with equivalent hands-on laboratory experience.
- Strong hands-on mammalian cell culture experience and flow cytometry expertise.
- Experience with cell-based functional or signaling assays; transferable GPCR assay experience may qualify if GLP-1R experience is absent.
- Experience with hemolysis or peptide membrane-toxicity assays; ability to work independently across multi-step assay timelines.
Nice to have
- Direct GLP-1R or incretin assay experience, or experience with stable receptor-expressing cell lines.
- Biacore (SPR), peptide handling, screening, or antimicrobial/antifungal susceptibility testing experience.
Pay
$110K - $165K USD base salary
Tools
CellTiter Blue, HTRF, ELISA, flow cytometry, cAMP, Biacore (SPR), PBMC
AI focus
Experimentally validate AI-generated peptide candidates and relay results to computational and AI teams to guide iterative candidate down-selection.
Model-written summary · the original posting is authoritative