Chai Discovery
Antibody Engineering
San Francisco office · On-site · Full-time · Posted Feb 15, 2026
- Education
- PhD or equivalent experience in the field.
About the job
Develop and experimentally evaluate de novo antibody designs, using laboratory results to improve AI models and support drug-discovery programs.
What you'll do
- Probe antibody design space for novel targets and formats, and validate designs in the lab.
- Run experimental programs at scale to guide, train, and evaluate next-generation models.
- Collaborate with AI researchers and pharma scientists on discovery programs.
What they ask for
- PhD or equivalent experience in Antibody Engineering, Computational Biology, or Protein Sciences.
- Hands-on experience designing and characterizing antibody-based biologics.
- Proficiency in molecular-biology workflows, binding and developability assays, and inspecting structures in PyMOL or similar tools.
- Strong communication, collaboration, and execution.
Tools
PyMOL
AI focus
Apply and evaluate de novo antibody design models; experimental programs guide, train, and evaluate next-generation models.
Model-written summary · the original posting is authoritative