D. E. Shaw Research
LLM Researcher and Engineer
$450K–$1000K
New York, NY · Full-time · Posted Oct 28, 2026
About the job
Develop and apply large language models to molecular science and drug discovery problems.
What you'll do
- Scale and optimize large-model training and inference workflows, including pre-training data pipelines and distributed or parallel training.
- Develop post-training techniques such as reinforcement learning, contrastive learning, and instruction tuning.
- Work on multimodal learning and integration of non-text modalities such as molecular graphs, 3D structures, and time series.
What they ask for
- Deep expertise in large-scale machine learning systems, LLM architecture and training, and/or multimodal learning.
- Strong Python programming skills.
Pay
$450,000–$1,000,000 USD annual base salary
Tools
Python
AI focus
Develop and apply LLMs for molecular science and drug discovery, covering pre-training, post-training, large-scale training and inference, and multimodal learning.
Model-written summary · the original posting is authoritative