Flagship Pioneering
FL114: Senior Scientist, Therapeutics Engineering
$126K–$160K
Cambridge, MA USA +1 · Senior · Full-time · Posted Sep 21, 2026
- Location
- Cambridge, MA USA
FL114 - Experience
- 2+ years of relevant experience in biotech or pharma.
- Education
- PhD in Cell or Molecular Biology, Biochemistry, or related disciplines.
About the job
Develop and optimize cellular screening assays and characterize novel biologics to support therapeutic programs and FL114’s epigenetic editing platform.
What you'll do
- Conduct, optimize, and troubleshoot cellular screening assays; characterize biologics using cell-based and molecular techniques.
- Develop assays and maintain plasmids or other materials for cell-based and cell-free assays; optimize and automate screening protocols.
- Identify and manage external partners, including CROs and CMOs.
What they ask for
- PhD in Cell or Molecular Biology, Biochemistry, or a related discipline, with 2+ years of relevant biotech or pharma experience.
- Hands-on expertise developing and optimizing cell-based and library screening assays; strong cellular and molecular biology background.
- Extensive experience in gene design, vector construction, and protein expression.
- Experience with routine and advanced molecular biology techniques, mammalian cell culture and transfection, and gene delivery technologies.
Nice to have
- Exposure to CRISPR-based or other gene-editing technologies; experience handling and interpreting NGS samples.
- Industry experience in drug discovery or pharmaceutical R&D.
Pay
$126,000 - $159,500 (base salary)
Tools
RT-qPCR, flow cytometry, liquid handling systems, plate readers, LNP, lentivirus, GraphPad Prism, Benchling
AI focus
Applicant data may be reviewed using AI-assisted screening tools; no AI-related job duties are stated.
Model-written summary · the original posting is authoritative