Flagship Pioneering
Principal AI Scientist, Autonomous Discovery
$208K–$286K
Cambridge, MA USA +1 · Principal · Full-time · Posted Sep 25, 2026
- Location
- Cambridge, MA USA
Pioneering Intelligence - Experience
- 5+ years of experience post PhD is stated as an alternative qualification pathway.
- Education
- PhD in a quantitative field (statistics, computer science, applied mathematics, computational biology, physics, or related), or equivalent demonstrated expertise.
About the job
Develops evolutionary algorithms and probabilistic methods for an autonomous-science platform to generate, evaluate, and improve populations of scientific and computational solutions.
What you'll do
- Design algorithms to evolve candidate populations at scale, maintaining diversity and measuring candidate quality.
- Develop Bayesian frameworks and benchmarks to evaluate populations and compare them with non-iterative baselines.
- Integrate algorithms into autonomous-science pipelines and contribute methods, prototypes, datasets, and publications.
What they ask for
- PhD in a quantitative field or equivalent demonstrated expertise with 5+ years of experience post PhD.
- Deep expertise in advanced Bayesian causal modeling and/or evolutionary programming.
- Ability to invent algorithms and deliver working, validated implementations; strong software engineering and large-scale computational experimentation skills.
- Scientific leadership demonstrated through top-tier publications, influential work, or widely adopted open-source tools.
Nice to have
- Experience applying these methods to biological, scientific, or mechanistic-modeling domains.
- Ability to set technical direction, collaborate across research and engineering, and mentor junior colleagues.
Pay
$208,000 - $286,000 (base salary)
Tools
Bayesian inference, reinforcement learning, optimization, probabilistic programming, genetic/evolutionary algorithms, quality-diversity methods
AI focus
Builds autonomous scientific search systems using evolutionary algorithms and Bayesian evaluation to discover, refine, and rank candidate solutions.
Model-written summary · the original posting is authoritative