Flagship Pioneering
Scientist, Machine Learning (Human Physiology)
$136K–$212K
Cambridge, MA USA +1 · Full-time · Posted Oct 28, 2026
- Location
- Cambridge, MA USA
FL127 - Education
- PhD in biomedical engineering, physiology, bioengineering, biophotonics, or a related field, or an MD/PhD; substantial applied machine learning experience required.
About the job
Connect physiological signals from a novel device platform to human physiology by designing studies and modeling how measurements relate to reference measures and outcomes.
What you'll do
- Ground measured signals in physiology, assess confounders, and review signals for plausibility.
- Co-design human studies, including endpoints, reference measurements, and protocols.
- Build and evaluate models on small cohorts, assess evidence quality, and report findings and limitations.
What they ask for
- PhD in biomedical engineering, physiology, bioengineering, biophotonics, or a related field, or an MD/PhD, with substantial applied machine learning experience.
- Deep knowledge of human physiology in a relevant area such as microcirculation, hemodynamics, tissue optics, skin biology, or cardiorespiratory physiology.
- Experience taking a measurement or digital biomarker through human studies, including endpoint selection, reference measurements, IRB-governed protocols, and agreement analysis.
- Statistical modeling on small human datasets, proficiency in Python and the modern ML stack, and comfort with an existing research codebase.
Nice to have
- Published or applied work in remote physiological sensing, digital biomarkers, or wearable or contactless measurement.
- Experience turning research results into a product feature; familiarity with skin optics models or modeling individual baselines and change over time.
Pay
$136,000 - $211,750 (base salary)
Tools
Python, Monte Carlo simulation, diffusion theory, chromophore decomposition
AI focus
Direct AI agents in daily work for literature synthesis, study design, data analysis, and code.
Model-written summary · the original posting is authoritative