Flagship Pioneering
Senior Scientist, Bioanalytical Sciences
$126K–$182K
Cambridge, MA USA +1 · Senior · Full-time · Posted Oct 7, 2026
- Location
- Cambridge, MA USA
Serif Biomedicines - Experience
- 5+ years of industry experience.
- Education
- Ph.D. in immunology, biochemistry, pharmaceutical sciences, cell biology, or a related field.
About the job
Leads bioanalytical assay development and studies to characterize immunogenicity, biodistribution, and other nonclinical endpoints for LNP-delivered nucleic acid therapies, while guiding junior scientists.
What you'll do
- Design, develop, qualify, validate, and execute immunogenicity, ligand-binding, flow cytometry, and other bioanalytical assays for nucleic acid therapies.
- Design and execute biodistribution and in vivo immunogenicity studies, and analyze and report data supporting nonclinical programs.
- Collaborate with cross-functional teams and mentor, coach, and manage junior scientists.
What they ask for
- Ph.D. in immunology, biochemistry, pharmaceutical sciences, cell biology, or a related field.
- Demonstrated expertise in innate immune signaling and DNA and mRNA nucleic acid sensing pathways.
- Proficiency in multicolor flow cytometry, ddPCR, ligand binding assays, leukopak processing, and PBMC isolation.
- Experience developing bioanalytical methods to measure drugs and biomarkers for LNP delivery of nucleic acid cargoes.
Nice to have
- Experience with LNPs and nucleic acid modalities.
- Experience managing junior scientists.
Pay
$126,000 - $181,500 (base salary; currency not stated)
Tools
LNPs, Flow Cytometry, ELISA, MSD, Luminex, bDNA, ddPCR
Model-written summary · the original posting is authoritative