Drimva

Flagship Pioneering

(Senior) Scientist - Translational Modeling & Decision Science

$115K–$205K

Cambridge, MA USA +1 · Senior · Full-time · Posted Jul 9, 2026

Location
Cambridge, MA USA
Pioneering Intelligence
Experience
3 to 7 years of industry experience.
Education
PhD in a life sciences discipline with quantitative experience, or in a quantitative life sciences discipline (pharmacometrics, systems pharmacology, computational biology, biomedical engineering, or equivalent).

About the job

Build mechanistic models and quantitative analyses to support translational drug-development and investment decisions across Flagship’s portfolio, while improving AI-platform outputs.

What you'll do

  • Deliver evidence-based translational predictions and recommendations for diligence, milestones, program decisions, and competitive assessments.
  • Identify relevant patterns and risks across programs and match analytical rigor to each decision’s context and consequences.
  • Evaluate AI-generated outputs, prototype modeling approaches, and turn findings into product requirements, benchmarks, and feedback for engineering teams.

What they ask for

  • PhD in a life sciences discipline with quantitative experience, or in a quantitative life sciences discipline (or equivalent), with strong knowledge of physiology, molecular biology, and immunology.
  • Demonstrated expertise building mechanistic models for drug-development decisions across multiple therapeutic areas.
  • Proficiency in Python scientific computing (scipy, numpy, pandas) and numerical ODE integration.
  • Experience operating across multiple concurrent programs and decision types; ability to communicate recommendations to non-technical decision-makers.

Nice to have

  • Experience applying frontier AI and LLM tools to drug-development decisions.
  • Translational breadth across drug modalities, familiarity with regulatory credibility frameworks, or experience in venture-backed or platform-company environments.

Pay

$115,000 - $205,000 USD base salary

Tools

Python, scipy, numpy, pandas, ICH M15, FDA MIDD

AI focus

Apply AI and LLM tools to drug-development decisions; evaluate autonomous outputs and provide domain-expert feedback, benchmarks, and product requirements to improve an agentic AI platform.

Model-written summary · the original posting is authoritative

First seen Oct 27, 2026 · Last verified Nov 5, 2026 (UTC)