Formation Bio
Senior / Principal Data Scientist, EHR AI
$186K–$267K
New York, NY +5 · Principal · Full-time · Posted Mar 30, 2026
- Location
- New York, NY
Boston, MA
San Francisco, CA
Raleigh-Durham, NC
116 Huntington Ave., Back Bay, Boston, MA, 02116
16 E 34th St., New York City, NY, 10016 - Experience
- 2+ years of industry or research experience; no separate years specified for Senior or Principal.
- Education
- PhD in computer science, biomedical informatics, statistics, epidemiology, or a related quantitative field (required).
About the job
Build predictive and causal models using longitudinal EHR, claims, and other real-world data to generate evidence that informs drug acquisition, indication selection, and trial design.
What you'll do
- Train, validate, and benchmark models for disease progression, treatment response, and patient outcomes; define cohorts and phenotypes.
- Apply causal methods and deliver RWE analyses to Business Development and R&D, communicating uncertainty and bias.
- Write reproducible code and collaborate with Engineering and Product; at Principal level, lead a modeling workstream and mentor scientists.
What they ask for
- PhD in computer science, biomedical informatics, statistics, epidemiology, or a related quantitative field.
- 2+ years of industry or research experience building machine learning models on EHR data, including linked claims or other real-world data, with substantiated results.
- Strong Python and deep learning expertise; familiarity with data lakes and distributed compute for large clinical datasets.
- Working knowledge of EHR and claims data, clinical vocabularies and common data models including OMOP CDM, and rigorous model evaluation.
Nice to have
- Experience with EHR foundation models or LLM-based patient timelines, causal inference, or LLM use for clinical text.
- Experience with OHDSI, linked EHR and biobank resources, pharma/biotech/health tech, or HEOR.
Pay
$185,500 - $232,000 (USD, total compensation range, Senior); $213,500 - $267,000 (USD, total compensation range, Principal)
Tools
Python, OMOP CDM, ICD-10, SNOMED CT, LOINC, RxNorm, ATC, LLMs
AI focus
Develop and evaluate predictive models, including EHR foundation models, and use LLMs for clinical data and text; apply causal methods to identify drugs that may modify disease course.
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