Freenome
Senior Development Scientist I
$140K–$200K
Brisbane, California +1 · Senior · Full-time · Posted Aug 18, 2026
- Location
- Brisbane, California
Brisbane, California, United States - Experience
- At least 4 years of professional life sciences experience with a PhD, or at least 10 years with a Bachelor’s or Master’s degree.
- Education
- PhD in molecular biology, biochemistry, genetics, or a related field; alternatively, a Bachelor’s or Master’s degree.
About the job
Develops and validates clinical-grade NGS assays for DNA and transfers robust workflows into regulated, high-throughput clinical production.
What you'll do
- Lead assay optimization, characterization, verification, and validation, including experimental strategy, execution, analysis, and reporting.
- Troubleshoot technical issues and improve assay performance and laboratory workflows.
- Partner with computational, engineering, and clinical laboratory teams to transfer protocols into production, including automation, validation, and SOP development.
What they ask for
- PhD in a related field with at least 4 years of life sciences experience, or a Bachelor’s or Master’s degree with at least 10 years of professional experience.
- Experience leading verification and validation studies for IVD assays in a regulated clinical laboratory environment (GLP).
- Hands-on experience developing automated NGS assays, including extraction, library preparation, target capture, and sequencing, and working with automated platforms and liquid handlers.
- Hands-on experience with nucleic acid preparation, amplification, and quantification, and ctDNA/cfDNA in NGS workflows.
Nice to have
- Clinical diagnostics and/or startup experience.
- Experience with methylated ctDNA/cfDNA; familiarity with Python or R, or contributions to publications, patents, or scientific innovations.
Pay
$140,250 - $200,025 USD base salary
Tools
Next-gen sequencing (NGS), PCR, qPCR, Qubit, Fragment Analyzer, Tapestation, Python, R
Model-written summary · the original posting is authoritative