Generate Biomedicines
Scientist I, Computational Protein Design
$140K–$196K
Somerville, MA +1 · Full-time · Posted Oct 21, 2026
- Location
- Somerville, MA
Somerville, Massachusetts, United States - Education
- PhD in protein engineering, biochemistry, bioengineering, molecular biology, computational biology, bioinformatics, or a related field.
About the job
Design therapeutic proteins and develop reusable computational workflows by integrating machine learning, experimental biology, and program data.
What you'll do
- Plan and execute protein design campaigns, translating therapeutic hypotheses into design strategies and data-generation plans.
- Connect computational design with experimental validation, interpret results, and communicate data-driven recommendations for program decisions.
- Identify recurring design needs and failure modes, and apply those learnings to improve methods, workflows, and platform capabilities.
What they ask for
- PhD in protein engineering, biochemistry, bioengineering, molecular biology, computational biology, bioinformatics, or a related field.
- Demonstrated experience formulating protein design strategy, such as de novo protein design, protein optimization, protein engineering, or antibody engineering.
- Strong practical understanding of protein sequence, structure, and their relationship to molecular properties and biological function.
- Experience with experimental design and interpreting complex biological datasets; working proficiency in Python and ability to develop reproducible analyses and computational workflows.
Nice to have
- Experience with machine learning or statistical modeling.
- Experience developing AI-agent workflows, workflow orchestration, or programmatic interfaces.
Pay
$140,000 — $196,000 USD per year (base salary)
Tools
Python
AI focus
Develop and apply agent-enabled computational workflows connecting scientific information, protein-design models, data, and tools; evaluate their outputs and reliability. Integrate AI-designed proteins with experimental data.
Model-written summary · the original posting is authoritative