Generate Biomedicines
Senior Machine Learning Scientist I/II, Model-Driven Optimization
$192K–$265K
Somerville, MA +1 · Senior · Full-time · Posted Jul 14, 2026
- Location
- Somerville, MA
Somerville, Massachusetts, United States - Education
- PhD in machine learning, computational biology, computer science, applied mathematics, engineering, or a related quantitative field.
About the job
Develops machine-learning methods and production systems for lab-in-the-loop therapeutic protein optimization, using experimental data to guide design and discovery.
What you'll do
- Develop optimization methods, property models, and data strategies for protein design and experimental campaigns.
- Build and maintain reliable ML models, software, data workflows, and LLM-enabled or agentic systems.
- Partner with scientists and engineers to integrate platform capabilities, guide technical direction, and deliver experimental impact.
What they ask for
- PhD in machine learning, computational biology, computer science, applied mathematics, engineering, or a related quantitative field.
- Practical experience with probabilistic machine learning, Bayesian optimization, active learning, experimental design, or related sequential decision-making approaches.
- Experience developing ML methods or systems for biological, biomedical, or experimental scientific data.
- Strong Python skills and experience with modern ML frameworks such as PyTorch, JAX, or similar tools.
Nice to have
- Experience in protein design, protein engineering, antibody engineering, biologics discovery, or drug development.
- Experience with multi-objective optimization, uncertainty calibration, model-guided experimental work, deep learning, or LLM agents.
Pay
$192,000 — $265,000 USD base salary per year
Tools
Python, PyTorch, JAX, LLM
AI focus
Builds machine-learning methods and LLM-enabled or agentic workflows to guide therapeutic protein design, experimental selection, and iterative optimization.
Model-written summary · the original posting is authoritative