Generate Biomedicines
Senior Scientist I, Protein Analytics & Biophysics
$125K–$165K
Somerville, MA +1 · Senior · Full-time · Posted Oct 19, 2026
- Location
- Somerville, MA
Somerville, Massachusetts, United States - Experience
- Ph.D. route: 4+ years of relevant research experience; M.S. route: 8+ years of relevant experience; equivalent experience may be considered.
- Education
- Ph.D. in biochemistry, biophysics, analytical chemistry, protein science, or a related discipline; or M.S. with equivalent experience considered.
About the job
Leads hands-on protein analytical and biophysical characterization, developing methods and interpreting data to support discovery programs and a machine-learning-powered platform.
What you'll do
- Execute and develop analytical, separation, binding, and biophysical workflows to assess protein quality and developability.
- Design experiments, troubleshoot methods, interpret results, and recommend follow-up studies for project teams.
- Provide technical leadership on assigned projects and contribute to emerging molecular barcoding, mass spectrometry, proteomics, and data-integration approaches.
What they ask for
- Ph.D. in a related discipline with 4+ years of relevant research experience, or M.S. with 8+ years; equivalent experience may be considered.
- Hands-on expertise in biophysical characterization of proteins, including developability assessments.
- Practical experience with protein separation science and chromatography.
- Ability to independently plan experiments, troubleshoot workflows, interpret data, and recommend next steps.
Nice to have
- Experience with SPR or related binding technologies; BLI or other kinetic and affinity-based assays are also valuable.
- Experience with mass spectrometry, proteomics, structural mass spectrometry, molecular barcoding, or related technologies.
Pay
$125,000 — $165,000 USD per year (base salary)
Tools
SPR, BLI, SEC, IEX, HIC, capillary electrophoresis, mass spectrometry, proteomics
AI focus
Supports a machine-learning-powered discovery platform and contributes to machine-learning-enabled data integration; collaborates with computational and machine-learning teams.
Model-written summary · the original posting is authoritative