Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation

What you'll do

• Define and execute model-based development strategies; plan, conduct, and report exposure-response, trial simulation, dose-selection, and population PK analyses.
• Apply modeling methods, including AI/ML-informed analyses, and present model-based strategies to internal governance boards and regulatory agencies.
• Contribute to clinical program design and regulatory documents, and promote model-informed development through cross-functional work and external collaboration.

What they ask for

• PhD in quantitative clinical pharmacology/pharmacometrics or a relevant life sciences discipline, plus modeling/simulation experience; a PharmD or Master degree in the same disciplines with an additional 4 years of relevant experience may be considered.
• 5+ years using mechanistic PKPD and longitudinal disease modelling; proficiency in NONMEM or R.
• 3+ years planning, performing, and reporting clinical-data analyses to industry and regulatory standards.
• Expertise applying AI/ML in clinical pharmacology and pharmacometric analyses.

Nice to have

• Prior experience in Oncology Research and Development.
• Strong record implementing Model-Informed Drug Development (MIDD) approaches.

Pay

$188,100 to $313,500 USD (annual base salary); EUR 119,250 to EUR 198,750 (annual gross base salary)

Tools

NONMEM, R, AI/ML

AI focus

Applies AI/ML and AI/ML-informed analyses to clinical pharmacology and pharmacometric analyses, using innovative methods to improve data use and trial efficiency.