GSK
Senior Director, Cardiovascular and Metabolic Diseases, Clinical Pharmacology Modeling and Simulation
$223K–$371K
USA - Massachusetts - Waltham +5 · Hybrid (Remote & On-site) · Director · Full-time · Posted Oct 29, 2026
- Location
- USA - Massachusetts - Waltham
GSK HQ
UK - Hertfordshire - Stevenage
Baar Onyx
USA - North Carolina - Durham
USA - Pennsylvania - Upper Providence - Experience
- 8+ years of industry experience in clinical pharmacology, modelling/simulation and drug development.
- Education
- PhD, MD, or PharmD.
About the job
Leads clinical pharmacology and model-informed drug development strategy and evidence generation across the drug development lifecycle, supporting cardiovascular and metabolic disease programs and regulatory submissions.
What you'll do
- Develop and implement MIDD and clinical pharmacology strategies; guide evidence generation and dosing decisions.
- Coordinate CPMS activities and cross-functional partnerships across the portfolio.
- Approve and review study designs, analyses, reports, and clinical pharmacology regulatory documents; provide scientific leadership through publications and presentations.
What they ask for
- PhD, MD, or PharmD.
- Experience in pharmacometrics and applying it to clinical questions in drug development.
- Experience working with senior stakeholders in a cross-functional environment.
- Experience in Cardiovascular and Metabolic Diseases therapy areas.
Nice to have
- Strong track record implementing Model-Informed Drug Discovery and Development (MIDD) approaches.
- Experience collaborating in multidisciplinary teams, communicating effectively, and delivering results on time.
Pay
USD $222,750 to $371,250 annual base salary
Tools
MIDD, QSP, AI/ML, FDA, EMA, CDE, PMDA, ICH
AI focus
Build partnerships with AI/ML functions and promote AI/ML integration in clinical pharmacology and MIDD.
Model-written summary · the original posting is authoritative