HeartFlow
Senior Systems Engineer
$180K–$215K
San Francisco, California +1 · Senior · Full-time · Posted Oct 9, 2026
- Location
- San Francisco, California
San Francisco - Experience
- 8+ years of industry experience in systems engineering or a related engineering role developing complex software-enabled products.
- Education
- Bachelor's, Master's, or Ph.D. degree in Systems Engineering, Computer Science, Biomedical Engineering, or a related field.
About the job
Own system-level design, architecture, requirements, and verification strategy for Heartflow’s software-enabled medical products, coordinating technical work across product development and post-market activities.
What you'll do
- Define system requirements and functional architecture, maintaining traceability to verification and validation evidence.
- Lead system integration, risk management, and system-level verification planning in collaboration with cross-functional teams.
- Drive technical trade-offs and improve systems engineering practices, including requirements management and SDLC processes.
What they ask for
- Bachelor's, Master's, or Ph.D. degree in Systems Engineering, Computer Science, Biomedical Engineering, or a related field.
- 8+ years of industry experience in systems engineering or a related engineering role developing complex software-enabled products.
- Experience defining system architectures, requirements, specifications, interfaces, and system-level verification strategies; working understanding of product risk management and design controls.
- Working knowledge of IEC 62304; experience with requirements management, issue tracking, documentation, or product lifecycle management tools (e.g., Jira, Ketryx).
Nice to have
- Experience developing FDA-regulated SaMD or medical imaging systems, or with cardiovascular imaging, CT, CCTA, or clinical software workflows.
- Experience with MBSE or formal architecture methods; familiarity with ISO 14971, ISO 13485, INCOSE practices, or FDA cybersecurity guidance.
Pay
$180,000 to $215,000 USD base salary
Tools
IEC 62304, Jira, Ketryx, Python, ISO 14971, ISO 13485
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