Iambic Therapeutics
Research Scientist I/II, Bioanalytical Sciences & Assay Development
$114K–$156K
San Diego HQ · Full-time · Posted Aug 31, 2026
- Experience
- Approximately 0–5 years with a Ph.D.; significant relevant industry experience with an M.S.
- Education
- Ph.D. in Bioanalytical Chemistry, Mass Spectrometry, Chemical Biology, Drug Metabolism/Pharmacokinetics, Pharmaceutical Sciences, Biochemistry, or a related discipline; or an M.S. with significant relevant industry experience.
About the job
Develops mass spectrometry-based assays and bioanalytical workflows that support hit identification, compound characterization, and AI-driven drug discovery.
What you'll do
- Develop MS-based HitID screening workflows, including ASMS, and develop bioanalytical, biochemical, ADME/DMPK, and physicochemical property assays.
- Optimize LC-MS/MS methods and automated, high-throughput workflows; support MS/LC-MS instrumentation and laboratory automation.
- Generate high-quality data and collaborate across research teams to inform compound design and optimization.
What they ask for
- Strong foundation in mass spectrometry, bioanalytical science, and assay development, preferably with hands-on LC-MS/MS experience.
- Demonstrated experience developing, optimizing, and troubleshooting bioanalytical, biochemical, or screening assays.
- Strong understanding of quantitative assay design, experimental controls, data quality, and troubleshooting.
- Ph.D. in a relevant discipline with approximately 0–5 years of relevant experience, or an M.S. with significant relevant industry experience.
Nice to have
- Experience with MS-based screening or HitID, including ASMS or related technologies.
- Experience with ADME/DMPK or physicochemical property assays, MS/LC-MS platforms, laboratory automation, or high-throughput experimentation.
Pay
$113.6K – $156K • Multiple Ranges
Tools
Mass spectrometry, LC-MS/MS, ASMS, SCIEX, Agilent, Thermo
AI focus
Generates experimental datasets supporting AI/ML-driven compound design and optimization, and collaborates with computational/AI teams.
Model-written summary · the original posting is authoritative