Iambic Therapeutics
Research Scientist I/II, Immunology
$113K–$156K
San Diego HQ · Full-time · Posted Aug 17, 2026
- Experience
- PhD or related pathway: 0–4 years of relevant experience; MS: 7+ years; BS: 9+ years.
- Education
- PhD in immunology or a related field, or another biological discipline with immunology-focused postdoctoral training; alternatively, MS or BS.
About the job
Designs and executes immunology studies to support small-molecule drug discovery, from target validation and hit-to-lead through candidate selection.
What you'll do
- Develop and run in vitro and ex vivo immune-cell assays and recurring compound-profiling studies.
- Analyze and communicate experimental results, including pharmacology, PK/PD, biomarker, and efficacy data.
- Support assay transfers, external studies, and laboratory operations.
What they ask for
- Strong knowledge of innate and/or adaptive immunology, immune-cell signaling, and disease-relevant mechanisms.
- Hands-on experience with in vitro and ex vivo immunology studies using primary immune cells, whole blood, or tissue-based systems; proficiency in multiparameter flow cytometry and cytokine/chemokine assays.
- Ability to develop, troubleshoot, and document robust cell-based assay cascades with appropriate controls and readouts.
- Experience supporting small-molecule discovery through compound screening or profiling.
Nice to have
- Experience transferring assays to CROs or automated/HTS platforms.
- Exposure to hit identification, hit-to-lead, or lead optimization; direct hands-on in vivo immunology experience is a plus.
Pay
$113K – $156K (base salary)
Tools
multiparameter flow cytometry, CROs, automated/HTS platforms, PK/PD
Model-written summary · the original posting is authoritative