Iambic Therapeutics
Sr Associate Scientist I or II, Medicinal Chemistry
$84K–$120K
San Diego HQ · Senior · Full-time · Posted Oct 5, 2026
- Experience
- BS: 5+ years in pharma/biotech; or MS: 3+ years in pharma/biotech. Preferred: 5+ years contributing to drug discovery projects.
- Education
- BS or MS in Chemistry.
About the job
Conduct laboratory-based medicinal chemistry and compound optimization for drug discovery, collaborating across teams and using machine-learning insights to guide the design–make–test cycle.
What you'll do
- Design, synthesize, purify, and characterize compounds; optimize reaction conditions and support parallel chemistry experiments.
- Analyze biological and ADME-PK data and contribute to data-driven project discussions and planning.
- Present results and collaborate with computational chemists to apply machine-learning insights to discovery and platform development.
What they ask for
- BS in Chemistry with 5+ years of pharma/biotech experience, or MS in Chemistry with 3+ years of pharma/biotech experience.
- Skills in multi-step organic synthesis, reaction optimization, SAR analysis, and scientific presentation.
- Availability to work onsite in San Diego.
Nice to have
- Prior exposure to high-throughput experimentation and familiarity with ADME-PK principles.
- Experience contributing to drug discovery projects; molecular modeling and structure-based drug design.
Pay
$84K – $120K (base salary)
Tools
LCMS, HPLC, NMR, cheminformatics tools, machine learning
AI focus
Collaborate with computational chemists to use machine-learning insights in the design–make–test cycle and platform development.
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