Drimva

Insitro

Senior Director, Project & Portfolio Management

$264K–$298K

South San Francisco, CA · Hybrid · Director · Full-time · Posted Jan 9, 2026

Experience
Minimum 15 years in biotech/pharmaceutical R&D and clinical development, including 8+ years in project/portfolio leadership.
Education
BS degree required in a life science field; MS or PhD preferred.

About the job

Leads insitro’s project and portfolio management organization, coordinating cross-functional teams and plans to advance drug candidates and establish AI-enabled portfolio decision and resource-allocation processes.

What you'll do

  • Build and lead an AI-forward PPM organization and partner with project leaders to develop strategies and high-performing teams.
  • Develop and execute integrated project plans spanning research, discovery, clinical development, software engineering, and data science/machine learning.
  • Partner with Compute, Operations, and Finance to establish agentic AI project-management, decision, and resource-allocation tools and methodologies.

What they ask for

  • BS degree in a life science field.
  • At least 15 years of biotech/pharmaceutical R&D and clinical development experience, including 8+ years in project/portfolio leadership of cross-functional matrix teams.
  • Extensive drug-development knowledge, including translational stages, CMC workflows, early commercial assessment, and clinical development from IND into Phase 2.
  • Exposure to designing and implementing agentic workflows in a pharma or biotech environment.

Nice to have

  • MS or PhD; Project Management Certification (PMP or equivalent).
  • Familiarity with Google Suite, Smartsheets, generative AI tools/LLMs, high-content human data modalities, or machine-learning-enabled drug discovery.

Pay

$264,000 - $298,000 USD base salary

Tools

Google Suite, Smartsheets, ChatGPT, Gemini, Claude

AI focus

Establish agentic AI project-management, decision, and resource-allocation tools and methodologies across the portfolio; exposure to agentic workflows is required.

Model-written summary · the original posting is authoritative

First seen Oct 27, 2026 · Last verified Nov 6, 2026 (UTC)