Insitro
Senior Director, Project & Portfolio Management
$264K–$298K
South San Francisco, CA · Hybrid · Director · Full-time · Posted Jan 9, 2026
- Experience
- Minimum 15 years in biotech/pharmaceutical R&D and clinical development, including 8+ years in project/portfolio leadership.
- Education
- BS degree required in a life science field; MS or PhD preferred.
About the job
Leads insitro’s project and portfolio management organization, coordinating cross-functional teams and plans to advance drug candidates and establish AI-enabled portfolio decision and resource-allocation processes.
What you'll do
- Build and lead an AI-forward PPM organization and partner with project leaders to develop strategies and high-performing teams.
- Develop and execute integrated project plans spanning research, discovery, clinical development, software engineering, and data science/machine learning.
- Partner with Compute, Operations, and Finance to establish agentic AI project-management, decision, and resource-allocation tools and methodologies.
What they ask for
- BS degree in a life science field.
- At least 15 years of biotech/pharmaceutical R&D and clinical development experience, including 8+ years in project/portfolio leadership of cross-functional matrix teams.
- Extensive drug-development knowledge, including translational stages, CMC workflows, early commercial assessment, and clinical development from IND into Phase 2.
- Exposure to designing and implementing agentic workflows in a pharma or biotech environment.
Nice to have
- MS or PhD; Project Management Certification (PMP or equivalent).
- Familiarity with Google Suite, Smartsheets, generative AI tools/LLMs, high-content human data modalities, or machine-learning-enabled drug discovery.
Pay
$264,000 - $298,000 USD base salary
Tools
Google Suite, Smartsheets, ChatGPT, Gemini, Claude
AI focus
Establish agentic AI project-management, decision, and resource-allocation tools and methodologies across the portfolio; exposure to agentic workflows is required.
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