Drimva

Insitro

Senior/ Staff Software Engineer, Imaging

$191K–$233K

South San Francisco, CA · Staff · Full-time · Posted Aug 25, 2026

Experience
6+ years.

About the job

Build and scale imaging data and ML infrastructure, tools, and workflows that enable scientists to run and analyze high-content biological screening experiments.

What you'll do

  • Design and scale platform capabilities and interactive tools for ML-powered imaging screens, data exploration, quality assessment, and visualization.
  • Take ML workflows from research prototypes to reliable production systems processing terabytes of data per day, with strong data integrity, lineage, reproducibility, and observability.
  • Partner with scientists and microscopy teams to translate research needs into software; own end-to-end projects and mentor engineers.

What they ask for

  • 6+ years of professional experience building and operating production-grade software and high-throughput data pipelines, primarily in Python.
  • Hands-on experience with a Python-first ML stack (PyTorch/Lightning), distributed compute, workflow orchestration, and cloud infrastructure at multi-terabyte scale.
  • Track record of owning complex systems from architecture through production operation.

Nice to have

  • Experience designing, building, and maintaining scientific computing pipelines, visualizations, and QC processes for large-scale biological datasets.

Pay

$191,000 - $233,000 USD base salary

Tools

Python, PyTorch/Lightning, Ray, Dask, Kubernetes, Argo, Airflow, redun

AI focus

Scale ML-powered high-content imaging workflows and support ML-derived phenotypes and agentic analysis for drug discovery.

Model-written summary · the original posting is authoritative

First seen Oct 27, 2026 · Last verified Nov 5, 2026 (UTC)