Isomorphic Labs
Research Leader (Toxicology), Cambridge, MA
Cambridge, MA +1 · Full-time · Posted Sep 11, 2026
- Location
- Cambridge, MA
Cambridge, Massachusetts, United States - Experience
- Extensive professional experience in a senior toxicology role; no number of years specified.
- Education
- Ph.D. in Toxicology, Pharmacology, Biology, or DVM/MD with relevant experience.
About the job
Leads toxicology safety assessment for drug discovery and development projects and helps build AI-based predictive toxicology capabilities.
What you'll do
- Develop safety assessment strategies, screening cascades, and regulatory packages for small molecules and biologics.
- Partner with Machine Learning colleagues to develop predictive toxicology models and generate or analyse supporting data.
- Manage CRO relationships and data-generation campaigns, author regulatory toxicology sections, and mentor junior team members.
What they ask for
- Ph.D. in Toxicology, Pharmacology, Biology, or DVM/MD with relevant experience.
- Board Certification.
- Senior toxicology experience across therapy areas in biotech or pharma, including successful IND/CTA filings for small molecules and biologics.
- Deep understanding of Global Regulatory Guidelines regarding safety assessment and experience partnering with Discovery and Clinical teams.
Nice to have
- Experience with peptides and other new modalities.
- Good understanding of machine learning techniques; familiarity with Python and KNIME.
Tools
Python, KNIME
AI focus
Help build an AI-first predictive toxicology platform, including identifying, generating, and analysing data to develop and improve models.
Model-written summary · the original posting is authoritative