NewLimit
Scientist, mRNA Analytical Development
$120K–$155K
South San Francisco +1 · Full-time · Posted Oct 20, 2026
- Location
- South San Francisco
South San Francisco, California, United States - Experience
- Ph.D. with 0–3 years of relevant industry experience, or M.S. with 5+ years, or B.S. with 7+ years.
- Education
- Ph.D. in analytical chemistry, biochemistry, molecular biology, chemical engineering, or a related field; alternatively, an M.S. or B.S. with the stated experience.
About the job
Establish and run analytical methods to characterize DNA templates and mRNA, supporting process development and clinical advancement.
What you'll do
- Develop, validate, and run analytical assays for DNA templates and mRNA, including investigating atypical results.
- Serve as the mRNA analytical lead for CMC teams; evaluate new analytical technologies.
- Document methods and results, support transfers and qualification at CDMOs, and manage outsourced testing as needed.
What they ask for
- Experience developing and qualifying a broad range of mRNA analytical methods.
- Hands-on experience executing and troubleshooting HPLC separations, capillary electrophoresis, and plate-based impurity assays such as qPCR or ELISA.
- Ability to independently design, execute, and troubleshoot experiments; analyze and present complex data; and write technical documents.
- Strong communication and organizational skills.
Nice to have
- Understanding of the analytical method lifecycle and phase-appropriate qualification.
- Experience with sequencing workflows, cell-based potency assays, LC-MS assays, or transferring methods to CDMOs.
Pay
$120,000-155,000 USD base salary
Tools
HPLC, IP-RP-HPLC, SEC, capillary electrophoresis, qPCR, ELISA, Sanger, Oxford Nanopore Technologies
Model-written summary · the original posting is authoritative