NewLimit
Senior Scientist / Scientist, In Vivo Pharmacology
$130K–$180K
South San Francisco +1 · Senior · Full-time · Posted Sep 4, 2026
- Location
- South San Francisco
South San Francisco, California, United States - Experience
- 5+ years for Scientist; 8+ years for Senior Scientist.
- Education
- Ph.D. in pharmacology, physiology, biology or a related field or equivalent industry experience.
About the job
Designs and interprets in vivo studies to evaluate epigenetic reprogramming therapeutics and guide preclinical candidate selection.
What you'll do
- Design, execute, and interpret in vivo pharmacology studies across disease models and therapeutic programs.
- Develop animal models and oversee study protocols and CRO/vendor relationships.
- Analyze pharmacology data and contribute to preclinical decisions and regulatory-enabling study design.
What they ask for
- Ph.D. in pharmacology, physiology, biology, or a related field, or equivalent industry experience.
- Experience designing and executing in vivo pharmacology studies in rodent models, including PK, PD, efficacy, and dose-range finding.
- Experience with study design, dosing regimens, route-of-administration selection, and interpreting in vivo data.
- Experience leading project workflows, mentoring junior laboratory staff, and contributing to a preclinical or clinical drug development program.
Nice to have
- Experience with liver biology, hepatic disease models, or hepatocyte-directed delivery; nucleic acid or viral vector delivery in vivo.
- Experience with GLP-enabling or IND-enabling study design; single cell genomics or pooled screening applied to in vivo readouts.
Pay
USD $130,000 to $180,000 base salary
Tools
PK/PD, CRO
Model-written summary · the original posting is authoritative