Novartis
Principal Scientist, Biomarker Assay Development Bench Scientist
$108K–$234K
Cambridge (USA) · Principal · Full-time · Posted Sep 14, 2026
- Experience
- 4+ years with a PhD or MD, or 8+ years with a BS/MS.
- Education
- PhD or MD, or BS/MS.
About the job
Develops and qualifies preclinical and clinical biomarker assays to support drug discovery, patient stratification, and development programs across disease areas.
What you'll do
- Design, develop, optimize, and qualify biomarker assays, including ligand binding assays, for target engagement, pharmacodynamics, and patient stratification.
- Conduct hands-on laboratory research, analyze and interpret data, and support assay implementation in preclinical and clinical studies.
- Collaborate with cross-functional teams and document, report, and present research findings.
What they ask for
- PhD or MD with 4+ years’ relevant experience, or BS/MS with 8+ years’ relevant experience.
- Hands-on experience designing and executing LBA assays.
- Experience in biomarker assay development and expertise in assay development, qualification, and implementation for preclinical and/or clinical studies across animal and human matrices.
- Proven ability to independently develop and execute biochemical and cellular assays for drug discovery.
Nice to have
- Postdoctoral Fellowship.
- Experience with multiomics and patient stratification; animal models, ex vivo assays, RNA assays, LC-MS, statistics, computational analysis, or CROs/external vendors.
Pay
$108,500 and $201,500 per year (base salary) for Principal Scientist I; $126,000 and $234,000 per year (base salary) for Principal Scientist II.
Tools
ELISA, MSD, RNA assays, LC-MS
Model-written summary · the original posting is authoritative