Novartis
Principal Scientist II - Pharmacology
$126K–$234K
Cambridge (USA) · Principal · Full-time · Posted Jul 9, 2026
- Experience
- 5-8 years of research experience as a postdoc or in the pharmaceutical/biotech industry.
- Education
- PhD
About the job
Leads preclinical in vivo pharmacology studies and develops cancer models to evaluate therapies and generate translational data for early-stage drug discovery.
What you'll do
- Design preclinical in vivo studies to test hypotheses, screen candidate molecules, and establish proof of concept for new modalities.
- Develop CDX, PDX, and syngeneic models to assess anti-tumor activity, PK/PD relationships, biomarkers, and translational questions.
- Manage associate-level scientists, collaborate with project teams, and analyze and present results.
What they ask for
- PhD with 5-8 years of research experience as a postdoc or in the pharmaceutical/biotech industry.
- Deep knowledge of antibody drug conjugates.
- Extensive experience with CDX and PDX xenograft tumor models and/or syngeneic models.
- Expertise in cell culture, PCR, ELISA, western blot, and flow cytometry.
Pay
$126,000 and $234,000 per year (base salary); $126,000.00 - $234,000.00 (base salary)
Tools
CDX, PDX, PCR, ELISA, western blot, flow cytometry, Prism, Excel
Model-written summary · the original posting is authoritative