Novartis
Research Scientist I or II, Oligonucleotide Chemistry
$67K–$124K
Cambridge (USA) · Full-time · Posted Aug 28, 2026
- Experience
- One to three years of laboratory experience in academic or industrial research environments.
- Education
- Bachelor of Science or Master of Science in Chemistry or a related scientific discipline.
About the job
Synthesizes, optimizes, purifies, and characterizes therapeutic oligonucleotides for RNA-based medicine research.
What you'll do
- Execute solid-phase oligonucleotide synthesis and purify and characterize products using chromatography and mass spectrometry.
- Develop and optimize synthesis, purification, and analytical methods; operate and troubleshoot laboratory instrumentation.
- Maintain SOPs and document and analyze experimental results in electronic laboratory notebooks.
What they ask for
- Bachelor of Science or Master of Science in Chemistry or a related scientific discipline.
- Hands-on experience with automated solid-phase synthesizers and therapeutic oligonucleotide synthesis workflows.
- Proficiency in oligonucleotide purification, characterization, and analysis using chromatography and mass spectrometry.
- Understanding of RNA therapeutics and their application in biological systems.
Nice to have
- Experience supporting oligonucleotide process development, optimization, or technology innovation initiatives.
- Scientific communication skills, including presenting findings to multidisciplinary teams.
Pay
66,800.00 - 124,000.00 USD Annual (base salary)
Tools
automated DNA and RNA synthesizers, chromatography, mass spectrometry, electronic laboratory notebook systems
Model-written summary · the original posting is authoritative