Senior Principal Scientist/Principal Scientist, Immune Engagers

What you'll do

• Identify and validate tumor-targeting strategies and lead biology strategy and execution for multidisciplinary discovery programs.
• Design and interpret mechanistic studies, integrate cross-functional perspectives, and present evidence-based recommendations at governance reviews.
• Lead and develop scientists, build collaborations, and contribute to immune-engager strategy and modality innovation.

What they ask for

• PhD in cancer biology, immunology, or a related discipline with 5+ years of relevant research and/or industry experience; or MS with 10+ years of relevant industry experience.
• Expertise in cancer biology and/or immunology, including tumor immunology, T-cell or myeloid-cell biology, and immune suppression in the tumor microenvironment.
• Proficiency in immune-cell functional assays and complex immunophenotyping, including in vitro and ex vivo assays and multiparameter flow cytometry.
• Experience in antibody, multispecific biologic, and/or immune-engager discovery within cross-functional teams; strong research publication track record.

Nice to have

• Leadership in T-cell or myeloid cell-engager discovery from target validation through IND-enabling or early clinical activities.
• Project-team leadership, next-generation engager innovation, and mentoring experience.

Pay

$126,000 - $234,000 per year (base salary); $132,300 - $245,700 per year (base salary)

Tools

multiparameter flow cytometry