Senior Scientist I/II, Hematology- Target Biology and Discovery

What you'll do

• Design and conduct studies on target identification, target validation, and mechanism of action using molecular and cellular approaches.
• Develop cellular assays and use disease-relevant hematologic models to address drug-discovery questions.
• Analyze and communicate results, contribute to project strategy, and maintain laboratory safety and documentation.

What they ask for

• Bachelor’s or master’s degree in biology, cellular or molecular biology, or a related scientific discipline.
• Hands-on experience designing, executing, and interpreting molecular and cellular biology experiments, including developing reproducible cellular assays.
• Proficiency in mammalian cell culture and molecular and protein-analysis methods such as cloning, qPCR, western blotting, and multiparameter flow cytometry.
• Ability to plan and troubleshoot experiments and communicate conclusions; strong scientific communication, organization, and collaboration skills.

Nice to have

• Experience with primary hematopoietic, immune, or patient-derived samples; CRISPR-based functional genomics; or medium- or high-throughput screening or profiling.
• Experience in pharmaceutical, biotechnology, or translational research, or familiarity with hematologic malignancies, particularly AML or MDS.

Pay

$93,800 - $174,200 (base salary); $98,700 - $183,400 (base salary)

Tools

CRISPR-based perturbation, gene knockdown/overexpression, chemical probes, western blotting, qPCR, imaging, cellular phenotyping, multiparameter flow cytometry