Xaira Therapeutics
Principal Scientist, Biology
$164K–$205K
South San Francisco, California, United States · Principal · Full-time · Posted Sep 8, 2026
- Experience
- 6+ years of relevant experience.
- Education
- PhD in Immunology or a related field.
About the job
Leads inflammation and immunology therapeutic programs through hands-on research, target evaluation, experimental strategy, and cross-functional scientific leadership.
What you'll do
- Set therapeutic program strategy, oversee in vitro and in vivo studies, and guide target validation and candidate development.
- Design and conduct primary-cell immune studies, including profiling and functional assays, and translate results into program recommendations.
- Mentor scientists and present findings to senior leadership and cross-functional teams.
What they ask for
- PhD in Immunology or a related field.
- Relevant experience in in vitro and ex vivo immunology, including primary immune assays, co-culture systems, target cell depletion assays, and high-parameter flow cytometry.
- Ability to independently define research strategy, plan and interpret complex experiments, and advance target hypotheses.
- Track record of impact through first-author publications, posters, and meeting presentations.
Nice to have
- Experience with single-cell RNA sequencing (scRNAseq), CRISPR/Cas9, and omics data analysis.
- Comfort using AI tools to support research design, data analysis, and daily workflows.
Pay
$164,000-$205,000 annually (base salary)
Tools
high-parameter flow cytometry, ELISA, MSD, Luminex, qPCR, RNA-seq, scRNAseq, CRISPR/Cas9
AI focus
Comfortably leverage AI tools to support research design, data analysis, and daily workflows.
Model-written summary · the original posting is authoritative