Xaira Therapeutics
Principal Scientist, Target Discovery & Portfolio Strategy
$164K–$205K
South San Francisco, California, United States · Principal · Full-time · Posted Oct 13, 2026
- Experience
- 6+ years of industry experience in drug discovery, target discovery, preclinical drug development, or translational drug development.
- Education
- PhD in immunology or a related field.
About the job
Identify and prioritize therapeutic targets and disease opportunities, using scientific evidence to shape Xaira’s drug discovery portfolio.
What you'll do
- Assess disease areas, unmet needs, mechanisms, patient subsets, and current treatments to identify opportunities.
- Integrate human genetics, multi-omics, patient data, and published research to evaluate and prioritize therapeutic targets.
- Develop target assessments and recommendations, track emerging science and competition, and lead discovery programs or platform initiatives.
What they ask for
- PhD in immunology or a related field.
- 6+ years of industry experience in drug discovery, target discovery, preclinical drug development, or translational drug development.
- Experience using human genetics, genome-scale multi-omics, and other human data alongside cell biology, disease biology, and clinical findings to evaluate therapeutic hypotheses.
- Strong scientific judgment, clear communication, and ability to guide cross-disciplinary decisions.
Pay
$164,000-$205,000 annually (base salary)
AI focus
Use AI tools to analyze multi-modal data; work with Xaira’s AI-enabled target discovery and antibody design platforms.
Model-written summary · the original posting is authoritative