Xaira Therapeutics
Scientist I/II, Functional Genomics
$110K–$155K
South San Francisco, California, United States · Full-time · Posted Jul 29, 2026
- Experience
- 0–4 years of industry or postdoctoral research experience.
- Education
- Ph.D. in Molecular Biology, Genetics, Cell Biology, or a related field.
About the job
Leads development of organoid models and CRISPR screening workflows to uncover genotype–phenotype relationships and support therapeutic discovery.
What you'll do
- Develop and scale organoid systems and screening protocols, ensuring robust, reproducible data generation.
- Partner with computational biology, AI/ML, and drug discovery teams to interpret and communicate functional genomics findings.
- Manage projects and cross-functional collaborations, and mentor junior staff.
What they ask for
- Ph.D. in Molecular Biology, Genetics, Cell Biology, or a related field.
- Hands-on experience developing and maintaining organoid models, including culture optimization, passaging, and characterization.
- Experience using CRISPR-based genetic perturbation in complex 3D or organoid models.
- Familiarity with adapting organoid systems to high-throughput screening formats, including automation or miniaturization.
Nice to have
- Familiarity with perturb-seq, single-cell genomics, or spatial omics.
- Experience with Python or R data analysis; broader in vivo or in vitro CRISPR screening experience.
Pay
$110,000 - $155,000 annually (base salary)
Tools
CRISPR, lentiviral, AAV, Python, R, perturb-seq
AI focus
Collaborates with AI/ML teams to analyze functional genomics datasets; the role is focused on organoid biology and screening, not developing AI models.
Model-written summary · the original posting is authoritative