Xaira Therapeutics
Senior Scientist, Antibody Characterization
$136K–$170K
South San Francisco, California, United States · Senior · Full-time · Posted Oct 7, 2026
- Experience
- PhD with 5+ years of industry experience, or BS/MS with 10+ years of industry experience; candidates with fewer years are encouraged to apply, and role leveling may be adjusted.
- Education
- PhD in a relevant discipline, or BS/MS degree in biophysics, biochemistry, structural biology, or a related discipline.
About the job
Performs hands-on antibody characterization and developability assessment to support discovery and development of therapeutic molecules.
What you'll do
- Characterize antibodies using high-throughput BLI and SPR to assess binding, kinetics, and affinity; screen for off-target binding.
- Conduct early developability assessments using SPR, DLS, DSF, SEC, and ELISA, and support related assay workflows and automation.
- Analyze and present experimental findings, maintain ELN records, and contribute to lab safety and operations.
What they ask for
- Extensive antibody-screening experience, including monoclonal, bispecific, and other antibody-like molecules.
- Extensive hands-on experience with ELISA, BLI, and SPR platforms, including Carterra or Biacore.
- Basic knowledge of protein production, purification, and characterization techniques, including affinity, ion exchange, HIC, DLS, DSF, and SEC.
- Proficiency with data analysis software such as GraphPad Prism and other statistical tools.
Pay
$136,000 - $170,000 annually (base salary)
Tools
BLI, SPR, Carterra, Biacore, ELISA, DLS, DSF, SEC
Model-written summary · the original posting is authoritative